Calculate expected number of events for Weibull distribution

Usage

.calculate_weibull_events(
  n_total,
  lambda_control,
  shape_control,
  hr,
  allocation_ratio,
  accrual_period,
  follow_up_period,
  dropout_rate
)

Arguments

n_total: Total sample size
lambda_control: Control group scale parameter
shape_control: Control group shape parameter
hr: Hazard ratio
allocation_ratio: Allocation ratio (control:treatment)
accrual_period: Patient accrual period (months)
follow_up_period: Additional follow-up period (months)
dropout_rate: Annual dropout rate

Value

List with expected events by group and total

Details

Uses numerical integration to calculate expected events under Weibull distribution Accounts for staggered entry, administrative censoring, and dropout