Multiple biomarker comparison dataset with 220 patients featuring three individual markers and a combined score for ROC analysis and marker comparison.
Format
A data frame with 220 rows and 6 variables:
- patient_id
Character: Patient identifier (PT001-PT220)
- diagnosis
Factor: "Positive" or "Negative" (35%/65% prevalence)
- marker1
Numeric: First biomarker (mean: 100 for positive, 70 for negative)
- marker2
Numeric: Second biomarker (mean: 85 for positive, 55 for negative)
- marker3
Numeric: Third biomarker (mean: 90 for positive, 65 for negative)
- combined_score
Numeric: Average of three markers
Details
Designed for comparing individual biomarker performance and evaluating combined marker strategies. The combined score typically shows improved discrimination compared to individual markers.
Examples
data(psychopdaROC_multibiomarker)
psychopdaROC(data = psychopdaROC_multibiomarker,
dependentVars = c("marker1", "marker2", "marker3", "combined_score"),
classVar = "diagnosis", positiveClass = "Positive",
clinicalMode = "comprehensive")
#> Error in psychopdaROC(data = psychopdaROC_multibiomarker, dependentVars = c("marker1", "marker2", "marker3", "combined_score"), classVar = "diagnosis", positiveClass = "Positive", clinicalMode = "comprehensive"): argument "refVar" is missing, with no default