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Comprehensive evaluation of biomarker predictive performance using both time-dependent and general binary ROC analysis. Supports multiple ROC estimation methods, statistical comparisons, and provides clinical interpretation of results.

Details

This analysis provides both time-dependent and binary ROC curve analysis with:

  • Time-dependent ROC: Multiple estimation methods (incident, cumulative, static)

  • Binary ROC: General diagnostic performance evaluation

  • DeLong test for comparing multiple ROC curves (binary mode)

  • Bootstrap and Venkatraman tests for ROC comparison

  • Bootstrap confidence intervals for robust inference

  • Optimal cutoff calculation using Youden index

  • Comprehensive visualization (ROC curves and AUC over time)

  • Clinical interpretation and performance assessment

  • Model comparison capabilities with statistical testing

Super classes

jmvcore::Analysis -> ClinicoPath::timerocBase -> timerocClass