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Oncology Clinical Trial Swimmer Plot Data

Source: R/data_swimmer_unified_docs.R
swimmer_unified_oncology.Rd

A realistic oncology clinical trial dataset demonstrating comprehensive swimmer plot analysis for regulatory submissions. Includes detailed clinical milestones, tumor characteristics, and biomarker information.

Usage

data(swimmer_unified_oncology)

Format

A data frame with 20 rows and 12 variables:

PatientID

Character. Unique patient identifiers (PT001-PT020)

StartTime

Numeric. Treatment start time (all patients start at 0)

EndTime

Numeric. Treatment end time in months (8-54 months)

BestResponse

Character. Best overall response per RECIST (CR, PR, SD, PD)

Surgery

Numeric. Time of surgery in months (1-7 months, NA if no surgery)

Biopsy

Numeric. Time of biopsy in months (0-4 months)

FirstResponse

Numeric. Time of first documented response (6-24 months, NA if no response)

Progression

Numeric. Time of disease progression (6-36 months, NA if no progression)

DeathLastFU

Numeric. Time of death or last follow-up (8-30 months, NA if alive)

TumorType

Character. Primary tumor type (Lung, Breast, Melanoma, Colon, Liver)

Stage

Character. Disease stage (IIA, IIB, IIIA, IIIB, IV)

Biomarker

Character. Relevant biomarker status (PD-L1+, HER2+, BRAF+, etc.)

Source

Generated for ClinicoPath package demonstration based on realistic oncology trial patterns

See also

Other swimmer plot datasets: swimmer_unified_basic, swimmer_unified_comprehensive, swimmer_unified_datetime, swimmer_unified_events

Examples

 
data(swimmer_unified_oncology)

# Comprehensive oncology swimmer plot
swimmerplot(
  data = swimmer_unified_oncology,
  patientID = "PatientID",
  startTime = "StartTime",
  endTime = "EndTime",
  responseVar = "BestResponse", 
  milestone1Name = "Surgery",
  milestone1Date = "Surgery",
  milestone2Name = "Biopsy",
  milestone2Date = "Biopsy",
  milestone3Name = "First Response",
  milestone3Date = "FirstResponse",
  milestone4Name = "Progression", 
  milestone4Date = "Progression",
  milestone5Name = "Death/Last FU",
  milestone5Date = "DeathLastFU",
  referenceLines = "protocol",
  showInterpretation = TRUE,
  personTimeAnalysis = TRUE,
  responseAnalysis = TRUE,
  plotTheme = "ggswim",
  sortOrder = "duration_desc"
)
#> 
#>  SWIMMER PLOT
#> 
#> character(0)
#> 
#>  Timeline Summary Statistics         
#>  ─────────────────────────────────── 
#>    Metric                Value       
#>  ─────────────────────────────────── 
#>    Number of Patients     20.00000   
#>    Total Observations     20.00000   
#>    Median Duration        31.50000   
#>    Mean Duration          30.80000   
#>    Total Person-Time     616.00000   
#>    Mean Follow-up         30.80000   
#>    CR Rate (%)            30.00000   
#>    PD Rate (%)            25.00000   
#>    PR Rate (%)            25.00000   
#>    SD Rate (%)            20.00000   
#>  ─────────────────────────────────── 
#> 
#> 
#>  <div style='background-color: #e8f5e8; padding: 15px; border-radius:
#>  5px; margin: 10px 0;'>
#> 
#>  Clinical Interpretation
#> 
#>  <div style='margin: 10px 0;'><h5 style='color: #2e7d32;'>Timeline
#>  Analysis:
#> 
#>  Study included 20 patients with 20 timeline observations. Median
#>  follow-up was 31.5 months (range: 8.0 to 54.0 months).
#> 
#>  <div style='margin: 10px 0;'><h5 style='color: #2e7d32;'>Person-Time
#>  Analysis:
#> 
#>  Total person-time: 616.0 months. Average follow-up per patient: 30.8
#>  months.
#> 
#>  <div style='margin: 10px 0;'><h5 style='color: #2e7d32;'>Response
#>  Pattern Analysis:
#> 
#>  Most common response was CR (30.0% of observations). Response
#>  distribution shows clinical patterns suitable for efficacy analysis.
#> 
#>  Person-Time Analysis                                                       
#>  ────────────────────────────────────────────────────────────────────────── 
#>    Response Type    Patients    Total Time    Mean Time    Incidence Rate   
#>  ────────────────────────────────────────────────────────────────────────── 
#>  ────────────────────────────────────────────────────────────────────────── 
#> 
#> 
#>  Milestone Event Summary                              
#>  ──────────────────────────────────────────────────── 
#>    Milestone    Events    Median Time    Time Range   
#>  ──────────────────────────────────────────────────── 
#>  ──────────────────────────────────────────────────── 
#> 
#> 
#>  Advanced Clinical Metrics                              
#>  ────────────────────────────────────────────────────── 
#>    Metric    Value    Unit    Clinical Interpretation   
#>  ────────────────────────────────────────────────────── 
#>  ────────────────────────────────────────────────────── 
#>